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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MSH6
All Species:
9.39
Human Site:
S611
Identified Species:
14.76
UniProt:
P52701
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P52701
NP_000170.1
1360
152786
S611
E
T
K
T
I
L
K
S
S
L
S
C
S
L
Q
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001113749
1360
152750
S611
E
T
K
T
I
L
K
S
S
L
S
S
S
L
Q
Dog
Lupus familis
XP_531814
1283
145094
T585
P
Q
V
L
K
G
M
T
S
E
S
D
S
L
G
Cat
Felis silvestris
Mouse
Mus musculus
P54276
1358
151058
G610
E
T
K
T
V
L
K
G
S
L
S
S
C
L
Q
Rat
Rattus norvegicus
XP_002726765
1361
151628
G613
E
T
K
T
V
L
K
G
S
L
S
S
C
L
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_419359
1466
164165
G717
D
T
Q
K
I
L
K
G
S
L
I
S
C
I
Q
Frog
Xenopus laevis
NP_001089247
1340
149481
S590
D
T
K
K
V
L
K
S
C
L
S
T
S
I
Q
Zebra Danio
Brachydanio rerio
NP_878280
1369
153213
K610
I
E
T
L
K
I
F
K
A
I
V
A
S
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUM0
1190
133117
V506
S
D
D
N
W
P
L
V
L
R
T
M
Q
S
D
Honey Bee
Apis mellifera
XP_392346
1120
127429
L436
A
C
I
K
E
S
L
L
R
E
S
Q
F
W
S
Nematode Worm
Caenorhab. elegans
NP_491163
1186
133609
K502
S
E
W
P
E
V
L
K
G
M
L
E
D
S
S
Sea Urchin
Strong. purpuratus
XP_797647
1335
149141
R583
Y
L
L
A
V
T
E
R
P
C
E
G
S
S
G
Poplar Tree
Populus trichocarpa
XP_002320307
1288
142120
L592
N
K
G
E
N
G
S
L
A
L
S
A
L
G
G
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04716
1324
146779
R584
R
T
I
V
R
Q
T
R
N
P
L
V
N
N
L
Baker's Yeast
Sacchar. cerevisiae
Q03834
1242
140062
E558
S
S
E
Y
F
S
T
E
E
D
W
P
E
V
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.3
88.1
N.A.
85.8
86.4
N.A.
N.A.
64.2
66.5
60
N.A.
39
41.2
34.4
48.6
Protein Similarity:
100
N.A.
98.6
91.3
N.A.
92.1
92.8
N.A.
N.A.
75.4
79.9
74.9
N.A.
57.6
58
52.7
66.6
P-Site Identity:
100
N.A.
93.3
26.6
N.A.
73.3
73.3
N.A.
N.A.
46.6
60
6.6
N.A.
0
6.6
0
6.6
P-Site Similarity:
100
N.A.
93.3
33.3
N.A.
80
80
N.A.
N.A.
66.6
80
26.6
N.A.
6.6
6.6
13.3
20
Percent
Protein Identity:
36.1
N.A.
N.A.
33.2
29
N.A.
Protein Similarity:
52
N.A.
N.A.
51.4
49.1
N.A.
P-Site Identity:
13.3
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
20
N.A.
N.A.
20
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
7
0
0
0
0
14
0
0
14
0
0
0
% A
% Cys:
0
7
0
0
0
0
0
0
7
7
0
7
20
0
0
% C
% Asp:
14
7
7
0
0
0
0
0
0
7
0
7
7
0
7
% D
% Glu:
27
14
7
7
14
0
7
7
7
14
7
7
7
0
0
% E
% Phe:
0
0
0
0
7
0
7
0
0
0
0
0
7
0
0
% F
% Gly:
0
0
7
0
0
14
0
20
7
0
0
7
0
7
20
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
7
0
14
0
20
7
0
0
0
7
7
0
0
14
0
% I
% Lys:
0
7
34
20
14
0
40
14
0
0
0
0
0
0
0
% K
% Leu:
0
7
7
14
0
40
20
14
7
47
14
0
7
34
20
% L
% Met:
0
0
0
0
0
0
7
0
0
7
0
7
0
0
0
% M
% Asn:
7
0
0
7
7
0
0
0
7
0
0
0
7
7
0
% N
% Pro:
7
0
0
7
0
7
0
0
7
7
0
7
0
0
0
% P
% Gln:
0
7
7
0
0
7
0
0
0
0
0
7
7
0
40
% Q
% Arg:
7
0
0
0
7
0
0
14
7
7
0
0
0
0
0
% R
% Ser:
20
7
0
0
0
14
7
20
40
0
54
27
40
27
14
% S
% Thr:
0
47
7
27
0
7
14
7
0
0
7
7
0
0
0
% T
% Val:
0
0
7
7
27
7
0
7
0
0
7
7
0
7
0
% V
% Trp:
0
0
7
0
7
0
0
0
0
0
7
0
0
7
0
% W
% Tyr:
7
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _